BYU Cougars It's all in the details 2021 record | 10-3 Opening week game | at USF, Sept. 3 Most important game of the season per ESPN | vs. Baylor, Sept. 10
Houston Cougars It's all in the details 2021 record | 12-2 Opening week game | at UTSA, Sept. 3 Most important game of the season per ESPN | at SMU, Nov. 5
Texas Longhorns It's all in the details 2021 record | 5-7 Opening week game | vs. Louisiana-Monroe, Sept. 3 Most important game of the season per ESPN | vs. Oklahoma, Oct. 8
Kentucky Wildcats It's all in the details 2021 record | 10-3 Opening week game | vs. Miami (OH), Sept. 3 Most important game of the season per ESPN | vs. Tennessee, Oct. 29
Cincinnati Bearcats It's all in the details 2021 record | 13-1 Opening week game | at Arkansas, Sept. 3 Most important game of the season per ESPN | at SMU, Oct. 22
Ole Miss Rebels It's all in the details 2021 record | 10-3 Opening week game | vs. Troy, Sept. 3 Most important game of the season per ESPN | vs. Alabama, Nov. 12
Pitt Panthers It's all in the details 2021 record | 11-3 Opening week game | vs. West Virginia, Sept. 1 Most important game of the season per ESPN | vs. West Virginia
Wisconsin Badgers It's all in the details 2021 record | 9-4 Opening week game | vs. Illinois State, Sept. 3 Most important game of the season per ESPN | at Iowa, Nov. 12
Arkansas Razorbacks It's all in the details 2021 record | 9-4 Opening week game | vs. Cincinnati, Sept. 3 Most important game of the season per ESPN | at Auburn, Oct. 29
Miami Hurricanes It's all in the details 2021 record | 7-5 Opening week game | vs. Bethune-Cookman, Sept. 3 Most important game of the season per ESPN | at Texas A&M, Sept. 17
Michigan State Spartans It's all in the details 2021 record | 11-2 Opening week game | vs. Western Michigan, Sept. 2 Most important game of the season per ESPN | at Michigan, Sept. 29
Oklahoma State Cowboys It's all in the details 2021 record | 12-2 Opening week game | vs. Central Michigan, Sept. 1 Most important game of the season per ESPN | at Oklahoma, Nov. 19
Oregon Ducks It's all in the details 2021 record | 10-4 Opening week game | vs. Georgia in Atlanta, Chick-fil-A Kickoff Game, Sept. 3 Most important game of the season per ESPN | vs. Utah, Nov. 19
USC Trojans It's all in the details 2021 record | 4-8 Opening week game | vs. Rice, Sept. 3 Most important game of the season per ESPN | at Utah, Oct. 15
NC State Wolfpack It's all in the details 2021 record | 9-3 Opening week game | at East Carolina, Sept. 3 Most important game of the season per ESPN | at Clemson, Oct. 1
Baylor Bears It's all in the details 2021 record | 12-2 Opening week game | vs. Albany, Sept. 3 Most important game of the season per ESPN | vs. Oklahoma State, Oct. 1
Oklahoma Sooners It's all in the details 2021 record | 11-2 Opening week game | vs. UTEP, Sept. 3 Most important game of the season per ESPN | vs. Texas, Oct. 8
Michigan Wolverines It's all in the details 2021 record | 12-2 Opening week game | vs. Colorado State, Sept. 3 Most important game of the season per ESPN | at Ohio State, Nov. 26
Texas A&M Aggies It's all in the details 2021 record | 8-4 Opening week game | vs. Sam Houston, Sept. 3 Most important game of the season per ESPN | at Alabama, Oct. 8
Utah Utes It's all in the details 2021 record | 10-4 Opening week game | at Florida, Sept. 3 Most important game of the season per ESPN | vs. USC, Oct. 15
Notre Dame Fighting Irish It's all in the details 2021 record | 11-2 Opening week game | at Ohio State, Sept. 3 Most important game of the season per ESPN | Ohio State
Clemson Tigers It's all in the details 2021 record | 10-3 Opening week game | at Georgia Tech, Sept. 5 Most important game of the season per ESPN | vs. NC State, Oct. 1
Georgia Bulldogs It's all in the details 2021 record | 14-1 Opening week game | vs. Oregon in Atlanta, Chick-fil-A Kickoff Game, Sept. 3 Most important game of the season, per ESPN | vs. Tennessee, Oct. 29
Ohio State Buckeyes It's all in the details 2021 record | 11-2 Opening week game | vs. Notre Dame, Sept. 3 Most important game of the season, per ESPN | vs. Michigan, Nov. 26
Alabama Crimson Tide It's all in the details 2021 record | 13-2 Opening week game | vs. Utah State, Sept. 3 Most important game of the season, per ESPN | vs. Texas A&M, Oct. 8